Synthesis of 3-benzyloxyl-17-maleyloxy-16, 17-secoestra- 1, 3, 5 (10)-triene-16-nitrile - Sinteza 3-benziloksi-17-maleiloksi- 16, 17-sekoestra-1, 3, 5 (10)-trien-16-nitrila
نویسندگان
چکیده
منابع مشابه
3 , 4 - Dihydroxy - 9 , 10 - secoandrosta - l , 3 , 5 ( 10 ) - triene = 9 , 17 dione 4 ,
Kinetic studies with 3,4-dihydroxy-9, IO-secoandrosta1,3,5(10)-triene-9,17-dione-4,5-dioxygenase gave intersecting initial velocity plots that conform to a sequential mechanism. Linear noncompetitive product inhibition patterns were observed with respect to either substrate, indicating the formation of a dead end complex. 4-Isopropyl catechol, a structural analogue of the organic substrate, inh...
متن کامل17-Deoxoestrone [estra-1,3,5(10)-trien-3-ol]–methanol (3/1)
Three independent mol-ecules of the title estrone derivative and a mol-ecule of methanol comprise the asymmetric unit of the title compound [systematic name: 13-methyl-6,7,8,9,11,12,13,14,15,16-deca-hydro-cyclo-penta-[a]phenanthren-3-ol-meth-an-ol (3/1)], 3C(18)H(24)O·CH(3)OH. Two of the estrone mol-ecules exhibit 50:50 disorder (one displays whole-mol-ecule disorder and the other partial disor...
متن کاملEnzymatic bromination of 16-dehydroestradiol 3-methyl ether 17-acetate to 16-alpha-bromoestrone 3-methyl ether.
A recent communication from these laboratories (S. L. Neidleman et al., Tetrahedron Letters 44:5337, 1966) described the bromination and chlorination of the steroidal f3-diketones, 16ketoprogesterone and 16-keto-A-norprogesterone, and the bromination of the steroidal j-ketolactone, 15-keto-1-dehydrotestololactone, by the chloroperoxidase of Caldariomycesfumago (F. S. Brown and L. P. Hager, J. A...
متن کاملSynthesis and characterization of 6-(hydroxymethyl)-14, 16-dimethyl-13, 14, 16, 17-tetrahydro-6H-13, 17-epiminodibenzo [e, l] [1, 4] dioxacyclotridecin-15 (7H)-one
Synthesis and characterization of 6-(hydroxymethyl)-14, 16-dimethyl-13, 14, 16, 17-tetrahydro-6H-13, 17-epiminodibenzo [e, l] [1, 4] dioxacyclotridecin-15 (7H)-oneABSTRACTNew 6-(hydroxymethyl)-14, 16-dimethyl-13, 14, 16, 17-tetrahydro-6H-13, 17-epiminodibenzo [e, l] [1, 4] dioxacyclotridecin-15 (7H)-one (2a) was synthesized in good yield by the Petrenko–Kritchenko reaction of 2, 2'-((3-hydroxyp...
متن کاملCrystal structure of 16-ferrocenylmethyl-3β-hydroxyestra-1,3,5(10)-trien-17-one: a potential chemotherapeutic drug
A new ferrocene complex, 16-ferrocenylmethyl-3β-hy-droxy-estra-1,3,5(10)-trien-17-one dimethyl sulfoxide monosolvate, [Fe(C5H5)(C24H27O2)]·C2H6OS, has been synthesized and structurally characterized by single-crystal X-ray diffraction techniques. The mol-ecule crystallizes in the space group P21 with one mol-ecule of dimethyl sulfoxide. A hydrogen bond links the phenol group and the dimethyl su...
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ژورنال
عنوان ژورنال: Matica Srpska Journal for Natural Sciences
سال: 2002
ISSN: 0352-4906,2406-0828
DOI: 10.2298/zmspn0201005j